Growth hormone deficiency can cause children to grow slowly, and ultimately their height is significantly lower than their peers .
Onset usually occurs after 1 year of age, and the main manifestation is that physical development is slower than children of the same age and same sex.
With age, the height is more obvious, and the childish face, also known as “baby face”, is mostly normal in intelligence development.
Go to the hospital to do growth hormone stimulation experiment, you can find the peak of growth hormone
Image source: Zhankuhailuo
Specifically, growth hormone deficiency can be divided into congenital and acquired.
Congenital growth hormone deficiency is the inadequate secretion of growth hormone by the pituitary gland; Acquired growth hormone deficiency is insufficient or relatively insufficient growth hormone secretion caused by various disease factors.
- Congenital growth hormone deficiency
After birth, children with congenital growth hormone deficiency may develop growth disorders within the first few months, but it may not be obvious until 6 to 12 months of age. At this time, the growth rate is obviously slow, and the length is often significantly lower than The average of children of the same age.
And the children will have bone age lag, consistent with height and age. But if combined with hypothyroidism, bone age and height are inconsistent.
In children with congenital severe growth hormone deficiency, only mildly born with a length below normal, they may not immediately have growth disorders.
This part of the child is born with a higher probability of prolapse of the hip (abnormal fetal position) and perinatal apnea, and the duration of hypoglycemia and jaundice (yellowing of the whole body skin and sclera) may prolong in the neonatal period.
In addition, when growth hormone deficiency is combined with adrenocortical hormone deficiency, there may be severe hypoglycemia.
Growth hormone deficiency combined with gonadotropin deficiency can easily lead to hypoplasia of the penis, cryptorchidism, and scrotum.
Image source: Zhankuhailuo
- Acquired growth hormone deficiency
Children exhibit severe growth disorders, lagging bone age, increased weight / height ratio (weight gain, but height growth is not obvious), higher fat content, slightly fatter body, obvious beer belly, small hands and feet, and a childish face Low level and prominent forehead.
The sound is childish, the hair growth is thin and thin.
The penis may be small, and puberty is usually delayed .
In addition, growth hormone can not only promote growth, but also play a very important role in bone metabolism.
In recent years, studies have suggested that patients with growth hormone deficiency are prone to osteoporosis and fractures .